This video hosted by Yikers.com is a demonstration of some cool new touch screen technology that immediately reminded me of the way that the characters on Star Trek (the new shows anyway) would interact with their computers (aside from speaking).
I’ve had some experience designing an application for touch screen use, and it’s quite a bit different from a mouse and keyboard interface. I hope the R&D departments at places like Microsoft and Google are working on next generation user interfaces that use touch and speech.
I predict that the keyboard and mouse will go the way of vinyl records and electric typewriters in 15 years or less (possibly much less). Your children’s children will grow up in a world without these archaic devices. 
